KDM2B Antibody, Biotin conjugated

Cusabio

KDM2B Antibody, Biotin conjugated

20

ELISA

Research Use Only

Polyclonal

Biotin

Rabbit

IgG

Histone demethylase that demethylates \Lys-4\ and \Lys-36\ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 \Lys-4\ and dimethylated H3 \Lys-36\ residue while it has weak or no activity for mono- and tri-methylated H3 \Lys-36\. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Human

-20°C or -80°C

12352203