Bio-Connect

KDM3A (N) Antibody, Rabbit Polyclonal

ORB67000
Biorbyt
TargetKDM3A
Product group Antibodies
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Overview

  • Supplier
    Biorbyt
  • Product Name
    KDM3A antibody
  • Delivery Days Customer
    16
  • Applications Supplier
    WB:1:1000-1:5000 WB
  • Gene ID55818
  • Target name
    KDM3A
  • Target description
    lysine demethylase 3A
  • Target synonyms
    [histone H3]-dimethyl-L-lysine(9) demethylase 3A; JHDM2A; JHMD2A; jmjC domain-containing histone demethylation protein 2A; JMJD1; JMJD1A; jumonji C domain-containing histone demethylase 2A; jumonji domain-containing protein 1A; lysine (K)-specific demethylase 3A; lysine-specific demethylase 3A; testis-specific protein A; TSGA
  • Protein IDQ9Y4C1
  • Protein Name
    Lysine-specific demethylase 3A
  • Scientific Description
    Rabbit polyclonal to KDM3A.Lysine-specific histone demethylase 3A (KDM3A) is a histone demethylase that specificallydemethylates Lys-9 of histone H3, thereby playing a central role in histone code. KDM3Apreferentially demethylates mono-and dimethylated H3 Lys-9 residue, with a preference fordimethylated residue, while it has weak or no activity on trimethylated H3 Lys-9. KDM3A is involvedin hormone-dependent transcriptional activation, by participating in recruient to androgen-receptortarget genes, resulting in H3 Lys-9 demethylation and transcriptional activation. KDM3A has beenimplicated in spermatogenesis by regulating expression of target genes such as PRM1 and P1,which are required for packaging and condensation of sperm chromatin. KDM3A is also involved inobesity resistance through regulation of metabolic genes such as PPARA and UCP1.
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203