KDM5B Polyclonal Antibody

Reddot Biotech

KDM5B Polyclonal Antibody

5

ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1.5 mg/ml

Unconjugated

KDM5B

lysine demethylase 5B

[histone H3]-trimethyl-L-lysine(4) demethylase 5B; cancer/testis antigen 31; CT31; histone demethylase JARID1B; JARID1B; jumonji, AT rich interactive domain 1B; jumonji/ARID domain-containing protein 1B; lysine (K)-specific demethylase 5B; lysine-specific demethylase 5B; MRT65; PLU1; PLU-1; PPP1R98; protein phosphatase 1, regulatory subunit 98; PUT1; putative DNA/chromatin binding motif; RBBP2H1A; RBP2-H1; retinoblastoma-binding protein 2 homolog 1; retinoblastoma-binding protein 2, homolog 1A

Rabbit

IgG

PLU-1 is a large (1,544 amino acid) nuclear protein that interacts with brain factor-1 (BF-1) and paired box 9 (PAX9), both of which are developmental transcription factors. PLU-1 belongs to the testis-cancer antigen group of proteins and is a member of the ARID family of DNA binding proteins. It is a multi-domain protein with strong transcriptional repression properties. PLU-1 shows restricted expression in adult tissues, with high expression in testis and transient expression in the pregnant mammary gland. Both the PLU-1 gene and the PLU-1 protein product are specifically upregulated in breast cancer. PLU-1 may be important in meiotic transcription because of its apparent association with chromatin.

Human, Mouse

-20°C

12352203