KDOAM-25

MedChem Express

KDOAM-25 [2230731-99-2]

10

2230731-99-2

Research Use Only

C15H25N5O2

307.39

KDOAM-25 is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor with IC50s of 71 nM, 19 nM, 69 nM, 69 nM for KDM5A, KDM5B, KDM5C, KDM5D, respectively. KDOAM-25 increases global H3K4 methylation at transcriptional start sites and impairs proliferation in multiple myeloma MM1S cells[1].

NC(C1=CC=NC(CNCC(N(CC)CCN(C)C)=O)=C1)=O

12352200