CgoaEGY7QQ2EIJnHAAAAAIWMuvY509.png
CgoaEGY7QQ2EIJnHAAAAAIWMuvY509.png
KDOAM-25 [2230731-99-2]
T11751
Overview
- SupplierTargetMol Chemicals
- Product NameKDOAM-25 [2230731-99-2]
- Delivery Days Customer72
- CAS Number2230731-99-2
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameKDOAM-25
- Molecular FormulaC15H25N5O2
- Molecular Weight307.39
- Scientific DescriptionKDOAM-25, a potent and highly selective inhibitor of histone lysine demethylases 5 (KDM5) with IC50 values of 71 nM for KDM5A, 19 nM for KDM5B, 69 nM for KDM5C, and 69 nM for KDM5D, enhances global H3K4 methylation at transcriptional start sites and reduces proliferation in multiple myeloma MM1S cells.
- Shelf life instruction3 years
- SMILESC(NCC(N(CCN(C)C)CC)=O)C1=CC(C(N)=O)=CC=N1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Tumber A, et al. Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells. Cell Chem Biol. 2017 Mar 16;24(3):371-380.Read more