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KDOAM-25 citrate [2448475-08-7]

KDOAM-25 citrate [2448475-08-7]

Research Use Only
T11750
TargetMol Chemicals
CAS Number2448475-08-7
Product group Chemicals
Molecular Weight499.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    KDOAM-25 citrate
  • Delivery Days Customer
    10
  • CAS Number
    2448475-08-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    KDOAM-25 citrate
  • Molecular Formula
    C21H33N5O9
  • Molecular Weight
    499.51
  • Scientific Description
    KDOAM-25 citrate is a potent and highly selective histone lysine demethylases 5 (KDM5) inhibitor, with IC50 values of 71 nM, 19 nM, 69 nM, and 69 nM for KDM5A, KDM5B, KDM5C, and KDM5D, respectively. Multiple myeloma MM1S cells treated with KDOAM-25 citrate show increased global H3K4 methylation at transcriptional start sites and impaired proliferation [1].
  • Shelf life instruction
    3 years
  • SMILES
    NC(C1=CC=NC(CNCC(N(CC)CCN(C)C)=O)=C1)=O.OC(CC(C(O)=O)(O)CC(O)=O)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200