KDOAM-25 trihydrochloride

TargetMol Chemicals

KDOAM-25 trihydrochloride

114

Chemical

Research Use Only

KDOAM-25 trihydrochloride

C15H28Cl3N5O2

416.77

KDOAM-25 trihydrochloride is a potent and highly selective inhibitor of histone lysine demethylase 5 (KDM5), targeting KDM5A (IC50: 71 nM), KDM5B (IC50: 19 nM), KDM5C (IC50: 69 nM), and KDM5D (IC50: 69 nM). It enhances overall H3K4 methylation at the transcription start site and hinders the proliferation of multiple myeloma [MM1S cells].

3 years

O=C(N)C1=CC(CNCC(N(CCN(C)C)CC)=O)=NC=C1.Cl.Cl.Cl

-20°C

12352200