Keap1-Nrf2-IN-23

MedChem Express

Keap1-Nrf2-IN-23

9

Research Use Only

C30H31ClN4O5

563.04

Keap1-Nrf2-IN-23 (compound 56) is an inhibitor of the Keap1-Nrf2 PPI (IC50=16.0 nM). Keap1-Nrf2-IN-23 binds to Keap1 with a Kd value of 3.07 nM. Keap1-Nrf2-IN-23 has oral activity[1].

O=C(N1CC2=CC=CC(C(CC(O)=O)C3=CC(OC)=C(N(C)N=N4)C4=C3)=C2CC1)C5=C(Cl)C=C(OC(C)C)C=C5

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