KHK-IN-1

MedChem Express

KHK-IN-1 [1303469-70-6]

10

1303469-70-6

Research Use Only

C21H26N8S

422.55

KHK-IN-1 (compound 8) is a selective and cell membrane permeable ketohexokinase ( KHK ) inhibitor ( IC 50 =12 nM; F=34%). KHK-IN-1 inhibits the production of F1P in HepG2 cell lysates ( IC>sub>50 =400 nM). KHK-IN-1 has potential for the study of diabetes and obesity [1] .

CSC(C=CC=C1)=C1NC2=NC(N3CCNCC3)=NC4=C2N=CN=C4NCC5CC5

12352200