KI-7

MedChem Express

KI-7 [1489263-00-4]

10

1489263-00-4

Research Use Only

99.16

C23H18N2O2

354.40

KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC50=445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC50s of 2390 nM and 2550 nM, respectively[1][2].

O=C(NC1=CC=CC=C1)C(C2=CN(CC3=CC=CC=C3)C4=C2C=CC=C4)=O

-20°C,2°C to 8°C

12352200