
WB analysis of human fetal small intestine tissue using GTX47316 KIAA0427 antibody at 0.2-1microg/ml.
KIAA0427 antibody, N-term
GTX47316
Overview
- SupplierGeneTex
- Product NameKIAA0427 antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID9811
- Target nameCTIF
- Target descriptioncap binding complex dependent translation initiation factor
- Target synonymsCBP80/20-dependent translation initiation factor; Gm672; KIAA0427
- HostRabbit
- IsotypeIgG
- Protein IDO43310
- Protein NameCBP80/20-dependent translation initiation factor
- Scientific DescriptionCTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203