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Immunohistochemistry of paraffin-embedded Human placenta tissue using KIF1C Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human placenta tissue using KIF1C Polyclonal Antibody at dilution 1:60
Immunohistochemistry of paraffin-embedded Human placenta tissue using KIF1C Polyclonal Antibody at dilution 1:60

KIF1C Polyclonal Antibody

Research Use Only
E-AB-11350
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    KIF1C Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA IHC
  • Certification
    Research Use Only
  • Concentration
    0.6mg/ml
  • Scientific Description
    The kinesins constitute a large family of microtubule-dependent motor proteins, which are responsible for the distribution of numerous organelles, vesicles and macromolecular complexes throughout the cell . Individual kinesin members play crucial roles in cell division, intracellular transport, and membrane trafficking events including endocytosis and transcytosis . KIF1C is a member of the KIF1/Unc104 family of kinesin-like proteins, which are involved in the transport of mitochondria or synaptic vesicles in axons . Human KIF1C maps to chromosome 17p13 and encodes a predicted 1,103 amino acid protein with abundant expression in heart and skeletal muscle . Tyrosine phosphorylation is a putative regulator of KIF1C mediated retrograde transport of Golgi vesicles to the endoplasmic reticulum. KIF1C is capable of forming homodimers and can noncovalently associate with 14-3-3 beta, gamma, epsilon and zeta . In mouse macrophages, KIF1C is required for anthrax lethal toxin resistance.
  • UNSPSC
    12352203