KIFAP3 Polyclonal Antibody
RD83101A
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetKIFAP3
Overview
- SupplierReddot Biotech
- Product NameKIFAP3 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID22920
- Target nameKIFAP3
- Target descriptionkinesin associated protein 3
- Target synonymsdJ190I16.1; FLA3; KAP-1; KAP3; KAP-3; kinesin-associated protein 3; small G protein GDP dissociation stimulator; SMAP; smg GDS-associated protein; Smg-GDS
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe small G protein GDP dissociation stimulator (smg GDS) is a regulator protein having two activities on a group of small G proteins including the Rho and Rap1 family members and Ki-Ras; one is to stimulate their GDP/GTP exchange reactions, and the other is to inhibit their interactions with membranes. The protein encoded by this gene contains 9 Armadillo repeats and interacts with the smg GDS protein through these repeats. This protein, which is highly concentrated around the endoplasmic reticulum, is phosphorylated by v-src, and this phosphorylation reduces the affinity of the protein for smg GDS. It is thought that this protein serves as a linker between human chromosome-associated polypeptide (HCAP) and KIF3A/B, a kinesin superfamily protein in the nucleus, and that it plays a role in the interaction of chromosomes with an ATPase motor protein. Several transcript variants encoding different isoforms have been found for this gene.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203