KIRA6 [1589527-65-0]

Biorbyt

KIRA6 [1589527-65-0]

16

1589527-65-0

Research Use Only

C28H25F3N6O

518.5329

KIRA6 is an ATP-competitive IRE1alpha kinase inhibiting RNase attenuator (KIRA) that allosterically inhibits IRE1alpha RNase kinase activity (IC50 = 0.6 microM) and prevents oligomerization.

FC(C1C([H])=C([H])C([H])=C(C=1[H])N([H])C(N([H])C1=C([H])C([H])=C(C2=C([H])C([H])=C([H])C([H])=C21)C1=C2C(N([H])[H])=NC([H])=C([H])N2C(C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=N1)=O)(F)F

12352200