KISS1R antibody
ORB106907
ApplicationsWestern Blot
Product group Antibodies
ReactivityHuman
TargetKISS1R
Overview
- SupplierBiorbyt
- Product NameKISS1R antibody
- Delivery Days Customer16
- ApplicationsWestern Blot
- Applications SupplierWB: 1:1000 WB
- CertificationResearch Use Only
- ClonalityPolyclonal
- Clone IDRB40407
- ConjugateUnconjugated
- Gene ID84634
- Target nameKISS1R
- Target descriptionKISS1 receptor
- Target synonymsAXOR12; CPPB1; G protein-coupled receptor 54; GPR54; G-protein coupled receptor OT7T175; HH8; HOT7T175; hypogonadotropin-1; kiSS-1 receptor; KISS-1R; kisspeptins receptor; metastin receptor
- HostRabbit
- IsotypeIgG
- Protein IDQ969F8
- Protein NameKiSS-1 receptor
- Scientific DescriptionRabbit polyclonal to KISS1R. Receptor for metastin (kisspeptin-54 or kp-54), a C-terminally amidated peptide of KiSS1. KiSS1 is a metastasis suppressor protein that suppresses metastases in malignant melanomas and in some breast carcinomas without affecting tumorigenicity. The metastasis suppressor properties may be mediated in part by cell cycle arrest and induction of apoptosis in malignant cells. The receptor is essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/KISS1R system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood. The receptor is also probably involved in the regulation and fine-tuning of trophoblast invasion generated by the trophoblast itself. Analysis of the transduction pathways activated by the receptor identifies coupling to phospholipase C and intracellular calcium release through pertussis toxin-insensitive G(q) proteins.
- ReactivityHuman
- UNSPSC12352203