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ProductsBack/KITLG Antibody
Western blot analysis of extracts from A549, A431, Hela and 3T3 cells using SCF Antibody.
Western blot analysis of extracts from A549, A431, Hela and 3T3 cells using SCF Antibody.
Western blot analysis of extracts from A549, A431, Hela and 3T3 cells using SCF Antibody.

KITLG Antibody

CSB-PA122514
Cusabio
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman
TargetKITLG
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Overview

  • Supplier
    Cusabio
  • Product Name
    KITLG Antibody
  • Delivery Days Customer
    20
  • Applications
    Western Blot, ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID4254
  • Target name
    KITLG
  • Target description
    KIT ligand
  • Target synonyms
    c-Kit ligand; DCUA; DFNA69; familial progressive hyperpigmentation 2; FPH2; FPHH; kit ligand; Kitl; KL-1; mast cell growth factor; MGF; SCF; SF; SHEP7; SLF; steel factor; stem cell factor
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP21583
  • Protein Name
    Kit ligand
  • Scientific Description
    Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. KITLG/SCF and KIT also transmit signals via GRB2 and activation of RAS, RAF1 and the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. KITLG/SCF and KIT promote activation of STAT family members STAT1, STAT3 and STAT5. KITLG/SCF and KIT promote activation of PLCG1, leading to the production of the cellular signaling molecules diacylglycerol and inositol-1,4,5-trisphosphate. KITLG/SCF acts synergistically with other cytokines, probably interleukins. Lu H.S., Clogston C.L., Wypych J. Arch. Biochem. Biophys. 298:150-158(1992)
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    12352203