KLK7/ELA2-IN-1

MedChem Express

KLK7/ELA2-IN-1

14

Research Use Only

C46H72N8O12

929.11

LM-030 (BPR277) is a potent kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2) inhibitor with IC50s of 6 nM and 55 nM, respectively(Example 4)[1]. LM-030 can be used for the study of Netherton syndrome[2].

CC[C@@H]([C@]1([H])N2C([C@@](CC[C@H]2O)([H])NC([C@@H](NC([C@H]([C@H](OC([C@](NC([C@@H](N(C1=O)C)CC3=CC=C(C=C3)O)=O)([H])[C@@H](C)CC)=O)C)NC([C@H](CCC(N)=O)NC(C(C)C)=O)=O)=O)CC(C)C)=O)=O)C

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