KN-62 [127191-97-3]
S7422
Overview
- SupplierSelleck Chemicals
- Product NameKN-62 [127191-97-3]
- Delivery Days Customer9
- CAS Number127191-97-3
- CertificationResearch Use Only
- Scientific DescriptionKN-62 is a potent and specific inhibitor of Ca2+/calmodulin-dependent protein kinase II (CaMKII) with Ki of 0.9 muM; also a non-competitive antagonist of the purinergic receptor P2RX7 (IC50 = 15 nM). It is selective for CaMKII relative to PKA, PKC and MLCK, but inhibits CaMKI and CaMKIV equally well, The Ki value of KN-62 for CaMK V is 0.8 muM.
- UNSPSC12352200