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ProductsBack/(KO Validated) ADRBK1 Polyclonal Antibody

(KO Validated) ADRBK1 Polyclonal Antibody

Research Use Only
RD82268A
Reddot Biotech
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGRK2
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    (KO Validated) ADRBK1 Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    Western Blot, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID156
  • Target name
    GRK2
  • Target description
    G protein-coupled receptor kinase 2
  • Target synonyms
    ADRBK1; adrenergic beta receptor kinase 1; BARK1; beta-adrenergic receptor kinase 1; BETA-ARK1; beta-ARK-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203