(KO Validated) LDHB Polyclonal Antibody

Reddot Biotech

(KO Validated) LDHB Polyclonal Antibody

5

Western Blot

Research Use Only

1 mg/ml

Unconjugated

LDHB

lactate dehydrogenase B

epididymis secretory protein Li 281; HEL-S-281; lactate dehydrogenase H chain; LDH heart subunit; LDH-B; LDHBD; LDH-H; L-lactate dehydrogenase B chain; renal carcinoma antigen NY-REN-46; testicular secretory protein Li 25; TRG-5

Rabbit

IgG

This gene encodes the B subunit of lactate dehydrogenase enzyme, which catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+ in a post-glycolysis process. Alternatively spliced transcript variants have been found for this gene. Recent studies have shown that a C-terminally extended isoform is produced by use of an alternative in-frame translation termination codon via a stop codon readthrough mechanism, and that this isoform is localized in the peroxisomes. Mutations in this gene are associated with lactate dehydrogenase B deficiency. Pseudogenes have been identified on chromosomes X, 5 and 13.

Human, Mouse, Rat

-20°C

12352203