Kobe0065 [436133-68-5]

Biorbyt

Kobe0065 [436133-68-5]

16

436133-68-5

Research Use Only

C15H11CLF3N5O4S

449.7922

Kobe0065 is a novel and effective small-molecule compound inhibiting Ras-Raf interaction by SBDD; exhibits potent activity to competitively inhibit the binding of H-Ras GTP to c-Raf-1 RBD with a Ki value of 46 +/- 13 microM.

ClC1C([H])=C(C([H])=C([H])C=1C([H])([H])[H])N([H])C(N([H])N([H])C1C(=C([H])C(C(F)(F)F)=C([H])C=1[N+](=O)[O-])[N+](=O)[O-])=S

12352200