KP-457 (GMP)
HY-110397G
Overview
- SupplierMedChem Express
- Product NameKP-457 (GMP) [1365803-52-6]
- Delivery Days Customer5
- CAS Number1365803-52-6
- CertificationResearch Use Only
- Molecular FormulaC21H24N2O7S2
- Molecular Weight480.55
- Scientific DescriptionKP-457 (GMP) is KP-457 (HY-110397) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture.KP-457 is a selective a disintegrin and metalloproteinase 17 ( ADAM17 ) inhibitor, with higher selectivity for ADAM17 than for other MMPs and ADAM10, and IC 50 s are 11.1 nM (ADAM17), 748 nM (ADAM10), 717 nM (MMP2), 9760 nM (MMP3), 2200 nM (MMP8), 5410 nM (MMP9), 930 nM (MMP13), 2140 nM (MMP14), and 7100 nM (MMP17), respectively [1] .
- SMILESCS(=O)(NCC1=CC=C(C(N(C=O)O)CS(=O)(C2=CC=C(OCC#CC)C=C2)=O)C=C1)=O
- UNSPSC12352200