KP 544

MedChem Express

KP 544

9

Research Use Only

C18H19ClN4O

342.82

KP 544 is a potent neurotrophic protein enhancer that amplifies nerve growth factor (NGF)-induced neurite outgrowth of PC12 cells and SH-SY5Y neuroblastoma cells. KP544 also enhances choline acetyltransferase activity. KP 544 selectively interact in the differentiation pathway downstream of MAPK in a manner that amplifies nerve growth factor and cyclic AMP effects and is also neuroprotective [1] .

O[C@H]1CC[C@H](NC2=NC(N)=NC=C2C#CC3=CC=C(Cl)C=C3)CC1

12352200