KRAS G12C inhibitor 61 [2300967-40-0]

TargetMol Chemicals

KRAS G12C inhibitor 61 [2300967-40-0]

16

Chemical

Research Use Only

KRAS G12C inhibitor 61

C31H33ClFN7O2

590.09

KRAS G12C inhibitor 61 (Example 3) demonstrates potent activity by inhibiting phospho-ERK 1/2 in MIA PaCa-2 cells, with an IC50 value of 9 nM, and is applicable in the research of pancreatic, colorectal, and lung cancers [1].

3 years

O=C1N(C=2C(C(=N1)N3C(C)CN(C(C=C)=O)C(C)C3)=CC(Cl)=C(N2)C4=C(F)C=CC=C4N)C5=C(C(C)C)N=CC=C5C

-20°C

51202000