KRAS G12D inhibitor 1 [2621928-43-4]

TargetMol Chemicals

KRAS G12D inhibitor 1 [2621928-43-4]

114

2621928-43-4

Chemical

Research Use Only

KRAS G12D inhibitor 1

C33H32F2N6O2

582.64

KRAS G12D inhibitor 1 (example 243) is an inhibitor of KRAS G12D, exhibiting an IC50 of 0.8 nM for KRAS G12D-mediated ERK phosphorylation [1].

3 years

Oc1cc(-c2ncc3c(nc(OC[C@@]45CCCN4C[C@H](F)C5)nc3c2F)N2C[C@@H]3CC[C@H](C2)N3)c2c(cccc2c1)C#C

-20°C

51202000