KRAS inhibitor-3

MedChem Express

KRAS inhibitor-3

10

Research Use Only

99.65

C25H27N5O

413.51

KRAS inhibitor-3 is an inhibitor of KRAS inhibitor. KRAS inhibitor-3 binds to WT and oncogenic KRAS mutants with high affinity ( K D : 0.28 microM for KRAS WT, 0.63 microM for KRAS G12C, 0.37 microM for KRAS G12D, 0.74 microM for KRAS Q61H). KRAS inhibitor-3 also disrupts interaction of KRAS with Raf [1] .

OCCN1CCN(CC1)C2=CC(C3=CC=CC=C3)=NC4=C(C(C)=NN42)C5=CC=CC=C5

-20°C,2°C to 8°C

12352200