KRAS inhibitor-38

MedChem Express

KRAS inhibitor-38

9

Research Use Only

C53H68ClF2N9O8S

1064.68

KRAS inhibitor-38 (Example 18) is a KRAS inhibitor that effectively suppresses the activity of KRAS G12C, KRAS G12D, and KRAS G12V in vivo[1].

CO[C@H](C1=[C@@](C=C(C=N1)N2CCOCC2)[C@@]3=C4CC(C)(COC([C@@H]5CCCN(C([C@H](CC6=NC(C7=CC4=C8C(CCCN83)=C7)=CS6)NC([C@@H](N(C(C9(CCN(CC9)C([C@@H](Cl)F)=O)F)=O)C)C(C)C)=O)=O)N5)=O)C)C

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