KRAS Polyclonal Antibody

Reddot Biotech

KRAS Polyclonal Antibody

5

Western Blot

Research Use Only

Polyclonal

2 mg/ml

Unconjugated

KRAS

KRAS proto-oncogene, GTPase

cellular c-Ki-ras2 proto-oncogene; cellular transforming proto-oncogene; CFC2; c-Ki-ras; c-Ki-ras2; c-Kirsten-ras protein; 'C-K-RAS; C-K-RAS; GTPase KRas; KI-RAS; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral proto-oncogene; K-Ras; K-Ras 2; K-ras p21 protein; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NS; NS3; OES; oncogene KRAS2; PR310 c-K-ras oncogene; RALD; RASK2; transforming protein p21; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog

Rabbit

IgG

KRAS,also called p21,is a member of the Ras superfamily of proteins. It is located on human chromosome 12,and contains four coding exons and a 5 non-coding exon (PMID: 12778136). KRAS is a membrane-anchored guanosine triphosphate/guanosine diphosphate (GTP/GDP)-binding protein and is widely expressed in most human cells. Like other members of the Ras family,the KRAS protein is a GTPase,and it is involved in intracellular signal transduction and mainly responsible for EGFR-signaling activation (PMID: 19117687). KRAS mutations have been found in various malignancies,including lung adenocarcinoma,mucinous adenoma,ductal carcinoma of the pancreas and colorectal carcinoma. KRAS has two isoforms,a and b.

Human, Mouse

-20°C

12352203