The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA202913(KSR1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA202913(KSR1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: x200)
KSR1 Antibody
CSB-PA202913
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetKSR1
Overview
- SupplierCusabio
- Product NameKSR1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID8844
- Target nameKSR1
- Target descriptionkinase suppressor of ras 1
- Target synonymskinase suppressor of Ras 1; KSR; RSU2
- HostRabbit
- IsotypeIgG
- Protein IDQ8IVT5
- Protein NameKinase suppressor of Ras 1
- Scientific DescriptionSeveral serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGF -activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGF stimulation.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203