L 189

Selleck Chemicals

L 189

9

Research Use Only

L 189 is a novel human DNA ligase inhibitor with IC50 of 5 muM, 9 muM and 5 muM for hLigI, hLigIII and hLigIV, respectively. L 189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L 189 specifically sensitizes cancer cells to DNA damage.

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