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L-2-Hydroxyglutaric acid (disodium) [63512-50-5]

Research Use Only
HY-W015114
MedChem Express
CAS Number63512-50-5
Product group Chemicals
Estimated Purity99.12
Molecular Weight192.08
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Overview

  • Supplier
    MedChem Express
  • Product Name
    L-2-Hydroxyglutaric acid (disodium) [63512-50-5]
  • Delivery Days Customer
    10
  • CAS Number
    63512-50-5
  • Certification
    Research Use Only
  • Estimated Purity
    99.12
  • Molecular Formula
    C5H6Na2O5
  • Molecular Weight
    192.08
  • Scientific Description
    L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].
  • SMILES
    O=C(O[Na])[C@@H](O)CCC(O[Na])=O
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200