L-2-Hydroxyglutaric acid (disodium) (Standard)

MedChem Express

L-2-Hydroxyglutaric acid (disodium) (Standard) [63512-50-5]

5

Research Use Only

L-2-Hydroxyglutaric acid (disodium) (Standard) is the analytical standard of L-2-Hydroxyglutaric acid (disodium). This product is intended for research and analytical applications. L-2-Hydroxyglutaric acid disodium is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid disodium can inhibit histone demethylases and hence promote histone methylation [1] . L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase ( Mi-CK ) activity with K m and K i of 2.52 mM and 11.13 mM, respectively [2] .

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