L-NIO (dihydrochloride)

MedChem Express

L-NIO (dihydrochloride) [159190-44-0]

10

159190-44-0

Research Use Only

97.0

C7H17Cl2N3O2

246.13

L-NIO dihydrochloride is a potent, non-selective and NADPH-dependent nitric oxide synthase (NOS) inhibitor, with K i s of 1.7, 3.9, 3.9 microM for neuronal (nNOS), endothelial (eNOS), and inducible (iNOS), respectively [1] [2] . L-NIO dihydrochloride induces a consistentfocal ischemic infarctin rats [2] .

N[C@@H](CCCNC(C)=N)C(O)=O.[H]Cl.[H]Cl

-20°C

12352200