L3MBTL1 antibody
GTX103793
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityC. Elegans, Human
TargetL3MBTL1
Overview
- SupplierGeneTex
- Product NameL3MBTL1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID26013
- Target nameL3MBTL1
- Target descriptionL3MBTL histone methyl-lysine binding protein 1
- Target synonymsdJ138B7.3; H-L(3)MBT; l(3)mbt protein homolog; l(3)mbt-like 1; L3MBTL; L3MBTL1, histone methyl-lysine binding protein; lethal (3) malignant brain tumor l(3); lethal(3)malignant brain tumor-like protein 1; ZC2HC3
- HostRabbit
- IsotypeIgG
- Protein IDQ9Y468
- Protein NameLethal(3)malignant brain tumor-like protein 1
- Scientific DescriptionThis gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityC. Elegans, Human
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control. Lu J et al., 2019 Jun, Nat NeurosciRead more