Bio-Connect

L3MBTL1 antibody

GTX103793
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityC. Elegans, Human
TargetL3MBTL1
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Overview

  • Supplier
    GeneTex
  • Product Name
    L3MBTL1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID26013
  • Target name
    L3MBTL1
  • Target description
    L3MBTL histone methyl-lysine binding protein 1
  • Target synonyms
    dJ138B7.3; H-L(3)MBT; l(3)mbt protein homolog; l(3)mbt-like 1; L3MBTL; L3MBTL1, histone methyl-lysine binding protein; lethal (3) malignant brain tumor l(3); lethal(3)malignant brain tumor-like protein 1; ZC2HC3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9Y468
  • Protein Name
    Lethal(3)malignant brain tumor-like protein 1
  • Scientific Description
    This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
  • Reactivity
    C. Elegans, Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control. Lu J et al., 2019 Jun, Nat Neurosci
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