Lac-Phe . acetate [N-Lactoyl-L-phenylalanine]

Bioss Antibodies

Lac-Phe . acetate [N-Lactoyl-L-phenylalanine] [183241-73-8]

16

Research Use Only

>95%

Lac-Phe is an exercise-inducible metabolite, also called exerkine, that suppresses feeding and obesity. Lac-Phe is increased heavily with exercise in mammals and acts to reduce food intake and potentially decrease overall body weight and fat mass. In diet-induced obese mice, pharmacological administration of Lac-Phe led to decreased food intake, adiposity and body weight, as well as improved glucose homeostasis, while movement and energy expenditure were not affected. The biosynthesis of Lac-Phe from lactate and phenylalanine occurs in CNDP2+ cells, including macrophages, monocytes and other immune and epithelial cells.

-20°C

12352200