IHC-P analysis of normal skin and skin cancer using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17686 stains epithelial basement membranes in normal skin, in a skin cancer tissue it strongly stains invading cancer cells or their cytoplasm. Upper panel : Normal skin tissue Lower panel : Skin cancer tissue
![IHC-P analysis of lung cancer (SCC) tissue using GTX17685 Laminin alpha 3A antibody [BG5] and GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17685 detected basement membrane (BM)-like structure surrounding tumor cells. GTX17686 detected not only BMs but also the cytoplasm of cancer cells. Upper panel : GTX17686 Lower panel : GTX17685](https://www.genetex.com/upload/website/prouct_img/normal/GTX17686/GTX17686_20190522_IHC-P_2_w_23060620_303.webp "IHC-P analysis of lung cancer (SCC) tissue using GTX17685 Laminin alpha 3A antibody [BG5] and GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17685 detected basement membrane (BM)-like structure surrounding tumor cells. GTX17686 detected not only BMs but also the cytoplasm of cancer cells. Upper panel : GTX17686 Lower panel : GTX17685")
![IHC-P analysis of invasive lung cancer (SCC and ADC) tissue using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17686 strongly detected cytoplasm of cancer cells at invasion fronts. Upper panel : SCC Lower panel : ADC](https://www.genetex.com/upload/website/prouct_img/normal/GTX17686/GTX17686_20190522_IHC-P_3_w_23060620_559.webp "IHC-P analysis of invasive lung cancer (SCC and ADC) tissue using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17686 strongly detected cytoplasm of cancer cells at invasion fronts. Upper panel : SCC Lower panel : ADC")
![IHC-P analysis of normal mammary gland and breast cancer using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17686 stains basement membranes surrounding mammary glands in normal tissue, whereas in a breast cancer tissue cytoplasmic accumulation of gamma 2pf or its fragments is detected with P2H. Upper panel : Normal mammary gland Lower panel : Breast cancer](https://www.genetex.com/upload/website/prouct_img/normal/GTX17686/GTX17686_20190522_IHC-P_w_23060620_166.webp "IHC-P analysis of normal mammary gland and breast cancer using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17686 stains basement membranes surrounding mammary glands in normal tissue, whereas in a breast cancer tissue cytoplasmic accumulation of gamma 2pf or its fragments is detected with P2H. Upper panel : Normal mammary gland Lower panel : Breast cancer")
![WB analysis of various samples using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. Small gamma 2 N-terminal fragments are seen below the gamma 2pf band (45 kDa), and 15-kDa bands corresponds to NE1-2 and NE2-3. Left : recombinant human gamma 2pf under reducing conditions, 10% gel Right : conditioned medium of VMRC-LCP lung cancer cells, gradient gel Dilution : 1:1000](https://www.genetex.com/upload/website/prouct_img/normal/GTX17686/GTX17686_20190522_WB_w_23060620_528.webp "WB analysis of various samples using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. Small gamma 2 N-terminal fragments are seen below the gamma 2pf band (45 kDa), and 15-kDa bands corresponds to NE1-2 and NE2-3. Left : recombinant human gamma 2pf under reducing conditions, 10% gel Right : conditioned medium of VMRC-LCP lung cancer cells, gradient gel Dilution : 1:1000")
IHC-P analysis of normal skin and skin cancer using GTX17686 Laminin gamma 2 chain (N-terminal region) antibody [P2H]. The GTX17686 stains epithelial basement membranes in normal skin, in a skin cancer tissue it strongly stains invading cancer cells or their cytoplasm. Upper panel : Normal skin tissue Lower panel : Skin cancer tissue
Laminin gamma 2 antibody [P2H]
GTX17686
ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
Overview
- SupplierGeneTex
- Product NameLaminin gamma 2 antibody [P2H]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDP2H
- ConjugateUnconjugated
- FormulationLiquid
- HostMouse
- IsotypeIgG2a
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Highly sensitive detection of invasive lung cancer cells by novel antibody against amino-terminal domain of laminin gamma2 chain. Miyazaki K et al., 2016 Dec, Cancer SciRead more