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Lanabecestat (hydrochloride)

HY-100740A
MedChem Express
Molecular Weight448.99
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Lanabecestat (hydrochloride)
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Molecular Formula
    C26H29ClN4O
  • Molecular Weight
    448.99
  • Scientific Description
    Lanabecestat (AZD-3293) hydrochloride is a potent BACE1 inhibitor that has been investigated for its potential as a modifying treatment for Alzheimers disease. Lanabecestat (hydrochloride) demonstrated significant dose- and time-dependent reductions in concentrations of amyloid beta peptides in plasma, cerebrospinal fluid, and brain. Lanabecestat (hydrochloride) was also shown to produce reductions in Abeta neuritic plaque burden without demonstrating clinical benefits or slowing the progression of Alzheimers disease pathophysiology.
  • SMILES
    CC#CC1=CC(C2=CC([C@@]34N=C(C)C(N)=N4)=C(C[C@@]53CC[C@@H](OC)CC5)C=C2)=CN=C1.Cl
  • UNSPSC
    12352200