Lanraplenib (succinate)

MedChem Express

Lanraplenib (succinate) [1800047-00-0]

10

1800047-00-0

Research Use Only

98.58

C23H25N9O.3/2C4H6O4

620.64

Lanraplenib succinate (GS-9876 succinate) is a highly selective and orally active SYK inhibitor ( IC 50 =9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib succinate (GS-9876 succinate) inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans [1] [2] [3] .

NC1=CN=CC(C2=CN3C(C(NC4=CC=C(N5CCN(C6COC6)CC5)C=C4)=N2)=NC=C3)=N1.O=C(O)CCC(O)=O

2°C to 8°C

12352200