Larotaxel
HY-125374
Overview
- SupplierMedChem Express
- Product NameLarotaxel [156294-36-9]
- Delivery Days Customer10
- CAS Number156294-36-9
- CertificationResearch Use Only
- Estimated Purity98.62
- Molecular FormulaC45H53NO14
- Molecular Weight831.90
- Scientific DescriptionLarotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel[1][2][3].
- SMILESO=C([C@]1([H])OC(C)=O)[C@@]23[C@@]([C@@H]([C@@]4(O)C(C)(C)C1=C([C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C4)C)OC(C6=CC=CC=C6)=O)([H])[C@]7([C@@](OC7)([H])C[C@@H]2C3)OC(C)=O
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200