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Larotaxel

HY-125374
MedChem Express
CAS Number156294-36-9
Product group Chemicals
Estimated Purity98.62
Molecular Weight831.90
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Larotaxel [156294-36-9]
  • Delivery Days Customer
    10
  • CAS Number
    156294-36-9
  • Certification
    Research Use Only
  • Estimated Purity
    98.62
  • Molecular Formula
    C45H53NO14
  • Molecular Weight
    831.90
  • Scientific Description
    Larotaxel (XRP9881) is a taxane analogue with preclinical activity against taxane-resistant breast cancer. Larotaxel (XRP9881) exerts its cytotoxic effect by promoting tubulin assembly and stabilizing microtubules, ultimately leading to cell death by apoptosis. It presents the ability to cross the blood brain barrier and has a much lower affinity for P-glycoprotein 1 than Docetaxel[1][2][3].
  • SMILES
    O=C([C@]1([H])OC(C)=O)[C@@]23[C@@]([C@@H]([C@@]4(O)C(C)(C)C1=C([C@H](OC([C@H](O)[C@H](C5=CC=CC=C5)NC(OC(C)(C)C)=O)=O)C4)C)OC(C6=CC=CC=C6)=O)([H])[C@]7([C@@](OC7)([H])C[C@@H]2C3)OC(C)=O
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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