Western blot analysis of extracts from 293 cells, using LAT (Ab-255) antibody.
Western blot analysis of extracts from 293 cells, using LAT (Ab-255) antibody.
LAT (Ab-255) Antibody
CSB-PA153832
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLAT
Overview
- SupplierCusabio
- Product NameLAT (Ab-255) Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID27040
- Target nameLAT
- Target descriptionlinker for activation of T cells
- Target synonyms36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; IMD52; LAT1; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells family member 1; p36-38; pp36
- HostRabbit
- IsotypeIgG
- Protein IDO43561
- Protein NameLinker for activation of T-cells family member 1
- Scientific DescriptionRequired for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules. Zhang W., Cell 92:83-92(1998). Martin J., Nature 432:988-994(2004).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203