The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA697830(LATS2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA697830(LATS2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200)
LATS2 Antibody
CSB-PA697830
TargetLATS2
Product group Antibodies
Overview
- SupplierCusabio
- Product NameLATS2 Antibody
- Delivery Days Customer20
- FormulationLiquid
- Gene ID26524
- Target nameLATS2
- Target descriptionlarge tumor suppressor kinase 2
- Target synonymskinase phosphorylated during mitosis protein; KPM; large tumor suppressor homolog 2; LATS (large tumor suppressor, Drosophila) homolog 2; LATS, large tumor suppressor, homolog 2; serine/threonine kinase KPM; serine/threonine-protein kinase kpm; serine/threonine-protein kinase LATS2; warts-like kinase
- Protein IDQ9NRM7
- Protein NameSerine/threonine-protein kinase LATS2
- Scientific DescriptionThis gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203