LBM22

MedChem Express

LBM22

9

Research Use Only

C28H22F2N6O2

512.51

LBM22 is a CDC2-like kinase 2 (CLK2) inhibitor with the IC50 of 3.9 nM. LBM22 has antiproliferative activity and inhibits serine/arginine-rich (SR) protein phosphorylation. LBM22 down-regulates the expression of Wnt-related proteins and anti-apoptotic proteins and can be used for study of non-small cell lung cancer[1].

FC1(F)CN(CC2=CN=CC(C3=CC4=C(NN=C4C5=NC(C6=CC=CO6)=C(C7=CC=CO7)N5)C=C3)=C2)CC1

12352200