LBT-999

MedChem Express

LBT-999

9

Research Use Only

C20H26FNO2

331.42

LBT-999 is a phenyltropane derivative used for positron emission tomography (PET) exploration of the dopamine transporter (DAT). It has high affinity binding to DAT on rat striatal membranes and human postmortem brain slices in vitro, high uptake in the striatum in rat and baboon models in vivo, and its binding can be blocked by specific compounds.

COC([C@@H]1[C@]2([H])N([C@](CC2)([H])C[C@@H]1C3=CC=C(C=C3)C)C/C=C/CF)=O

12352200