LC3-mHTT-IN-AN1 [486443-73-6]

MedChem Express

LC3-mHTT-IN-AN1 [486443-73-6]

10

486443-73-6

Research Use Only

98.99

C15H9Br2NO3

411.04

LC3-mHTT-IN-AN1 (Compound AN1) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].

BrC1=CC=C(C/2=C1)NC(C2=C/C3=CC(Br)=C(C(O)=C3)O)=O

2°C to 8°C,-20°C

12352200