LC3-mHTT-IN-AN2 [7758-73-8]

MedChem Express

LC3-mHTT-IN-AN2 [7758-73-8]

10

7758-73-8

Research Use Only

96.05

C15H10O4

254.24

LC3-mHTT-IN-AN2 (Compound AN2) is a mHTT-LC3 linker compound, which interacts with both mutant huntingtin protein (mHTT) and LC3B but not with wtHTT or irrelevant control proteins. LC3-mHTT-IN-AN2 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons[1].

OC1=C2C(OC(C=C2C3=CC=CC=C3)=O)=CC(O)=C1

2°C to 8°C,-20°C

12352200