LDHA/PDKs-IN-2

MedChem Express

LDHA/PDKs-IN-2

10

Research Use Only

C17H20N2O5

332.35

LDHA/PDKs-IN-2 (compound 20k) is a potent and dual inhibitor of PDKs and LDHA with IC50s of 1.6 and 0.7 microM, respectively. LDHA/PDKs-IN-2 reduces A549 cell proliferation with an EC50 of 15.7 microM and decreases the lactate formation, and increases oxygen consumption. LDHA/PDKs-IN-2 has the potential for the research of cancer diseases.

CC1=C(C(C=CO1)=O)OCCN2CCN(CC2)C(C3=CC=CO3)=O

See Manual

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