LDN-214117 [1627503-67-6]

Biorbyt

LDN-214117 [1627503-67-6]

16

1627503-67-6

Research Use Only

C25H29N3O3

419.5161

LDN-214117 is a potent and selective ALK2 inhibitor with IC50 of 22 nM; > 100 fold selectivity for ALK5; also inhibits BMP6(IC50=100 nM).

O(C([H])([H])[H])C1C(=C(C([H])=C(C=1[H])C1=C(C([H])([H])[H])N=C([H])C(=C1[H])C1C([H])=C([H])C(=C([H])C=1[H])N1C([H])([H])C([H])([H])N([H])C([H])([H])C1([H])[H])OC([H])([H])[H])OC([H])([H])[H]

12352200