LDN-57444 [668467-91-2]
27706
CAS Number668467-91-2
Product group Chemicals
Estimated Purity≥98%
Molecular Weight397.6 Da
Overview
- SupplierBPS Bioscience
- Product NameLDN-57444 [668467-91-2]
- Delivery Days Customer7
- CAS Number668467-91-2
- CertificationResearch Use Only
- Estimated Purity≥98%
- Molecular FormulaC17H11Cl3N2O3
- Molecular Weight397.6 Da
- Scientific DescriptionLDN-57444 is a cell permeable ubiquitin C-terminal hydrolase (UCH-L1) inhibitor (Ki=0.4 microM). Decreases proteasome activity and increases levels of ubiquitinated proteins. Induces apoptosis and causes dramatic alterations in synaptic protein distribution and spine morphology in vivo. LDN-57444 is a useful tool to study UCH-L1 in different pathological conditions such as cancer and neurodegeneration.
- UNSPSC12352200