Lefty1 antibody [8B65]

GeneTex

Lefty1 antibody [8B65]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

8B65

500 ug/ml

Unconjugated

Lefty1

left right determination factor 1

AI450052; Eba; Ebaf; Left; Leftb; left-right determination factor 1; left-right determination, factor B; lefty; lefty-; lefty-1; protein lefty-1; St; stimulated by retinoic acid gene 3 protein; Stra3; Tgfb4; TGF-beta-4; transforming growth factor beta-4

Rat

IgG2

Left-right determination factor 1

This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. Mice lacking a functional copy of this gene exhibit embryonic lethality and defects in left-right patterning. [provided by RefSeq, Aug 2016]

Mouse

-20°C or -80°C,2°C to 8°C

12352203