LEK 8804

MedChem Express

LEK 8804

9

Research Use Only

C19H19N3O

305.37

LEK 8804 is a compound with 5-HT1A receptor agonist and 5-HT2 receptor antagonist properties, and has the activity of modulating related receptor-mediated behavioral responses. LEK 8804 can induce spontaneous tail-flick response in rats in a dose-dependent manner, showing complete 5-HT1A agonist activity, and can inhibit 5-HTP-induced head twitch response in mice, probably through antagonism of 5-HT2 receptors rather than agonism of 5-HT1A receptors.

[H][C@]1(C2)N(C[C@@H](C=C1C3=CC=CC4=C3C2=CN4)C(NCC#C)=O)C

12352200